Tirzepatide was initially formulated as a treatment for Type 2 diabetes. However, due to its powerful effects on weight regulation, it has rapidly gained recognition as one of the most effective anti-obesity medications available today.

This innovative medication works as a dual agonist of both the GLP-1 (glucagon-like peptide-1) and GIP (glucose-dependent insulinotropic polypeptide) receptors. By stimulating these two key hormonal pathways, tirzepatide helps control blood sugar levels, curbs appetite, enhances metabolic efficiency, and promotes consistent, long-term weight loss. It not only helps individuals lose weight but also supports improved energy balance and overall metabolic health.

• GLP-1: Suppresses appetite and increases feelings of fullness after eating.
• GIP: Promotes insulin secretion and supports energy balance through receptors in the hypothalamus.

• Average weight loss of 24.7% after 72 weeks
• Reduces appetite and cravings
• Enhances satiety and energy balance
• Supports fat oxidation and metabolism
• Improves insulin sensitivity and blood sugar control

(often mild and temporary; affected only ~25% in trials)

• Injection site reaction (redness, swelling, itching)
• Nausea
• Vomiting
• Diarrhea
• Constipation
• Decreased appetite
• Fatigue
• Dyspepsia (indigestion)
• Abdominal pain
• Burping (may have sulfur smell)
• Hair loss

• Thyroid C-Cell Tumors
• Pancreatitis
• Gastroparesis (stomach paralysis)
• Hypoglycemia (if used with insulin)
• Gallbladder disease
• Kidney issues (linked to dehydration)
• Pulmonary aspiration under anesthesia 

        - ALWAYS disclose Tirzepatide use to surgical teams

• Do NOT use if pregnant or breastfeeding
• Do NOT use with a personal or family history of Medullary Thyroid Carcinoma or MEN 2 (Multiple Endocrine Neoplasia)
• Do NOT use if you have Type-1 diabetes, diabetic retinopathy, or severe GI disease
• Do NOT use if you are allergic or hypersensitive to Tirzepatide

Habits to Maximize Your Tirz Results

• While taking tirz, focus on meals rich in protein, fiber, and healthy fats—even if your appetite is low. Avoid greasy or sugary foods that can trigger nausea, and drink plenty of water throughout the day.
  
• Add light movement like walking or stretching 3–5 times a week, and include strength training a few times weekly to help maintain muscle. Staying active not only boosts your results but also helps with common side effects like constipation.
  
• Aim for 7–9 hours of sleep each night, as poor rest can slow progress and increase cravings. Try to stick to a consistent sleep schedule, and consider injecting in the evening if nausea is affecting your sleep.

  When Will I See Result

• Most people begin to see early changes ike reduced appetite or less frequent cravings within the first 1 to 2 weeks of consistent weekly injections.
  
• Noticeable weight loss typically becomes visible by weeks 4 to 8, especially when paired with movement and mindful eating. 
• Clinical studies on tirzepatide show
  
• 5% body weight reduction by week 12
  
• 10–20% total weight loss over 6 to 12 months with continued use
  
• Results vary depending on your dose, consistency, metabolism, and lifestyle habits.

How to Inject Peptides

• Clean vial top with alcohol pad.
  
• Remove syringe cap, insert needle into vial, and draw the prescribed dose.
  • If it draws slowly, inject a little air into the vial first.
    
• Cap syringe and set it on your clean prep surface.
  
• Clean injection site with alcohol pad, pinch skin, and insert needle quickly.
  
• Push plunger fully, wait a few seconds, then remove needle and dispose properly.
  
• Rub the site gently (through clothing) for 1 minute to aid absorption.
  
• Store peptide vial back in the refrigerator.

Best Locations for 

Subcutaneous Injections

Tirzepatide is injected subcutaneously into fatty tissue. Common sites include:

• Stomach (at least 2 inches from your belly button)
• Front of the thigh
• Back of the upper arm
  *Alternate injection sites each week to reduce irritation.